The NFL is entering its second week of preseason action, and top-rated sportsbooks are dealing odds on every game starting with Eagles vs. Patriots on Thursday night.
The majority of games will be played on Saturday prior to Packers vs. Broncos and Saints vs. 49ers on Sunday. Here we examine point spreads, moneylines and OVER/UNDERs on top sportsbook apps for Week 2 of the NFL Preseason.
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Odds for NFL Preseason Week 2 slate
Let's start with Eagles vs. Patriots on TNF. Please note that lines for all of these games will fluctuate as news surfaces about how much playing time key players, particularly quarterbacks, will get.
Eagles vs. Patriots spread, moneyline, total
New England QB Drake Maye saw limited action in last Thursday's preseason opener against Carolina. Maye completed two of three passes for 19 yards in the 17-3 victory. Check out Eagles vs. Patriots odds at BetMGM.
| BetMGM odds | Spread | Moneyline | Total |
| Eagles | +2.5 | +115 | OVER 35.5 |
| Patriots | -2.5 | -140 | UNDER 35.5 |
The Eagles opened up the preseason with a 16-13 win at Baltimore. Kenny Pickett saw the majority of work at QB, and starter Jalen Hurts did not play.
Pickett completed 14 of 22 passes for 89 yards and a TD to former Clemson running back Will Shipley. Kicker Jake Elliott made a 49-yard field goal as time expired to secure the win.
The Patriots played their first game since 2000 without Bill Belichick as head coach in the win over Carolina. New England was dominant defensively in Jerod Mayo’s head coaching debut. The Pats recorded five sacks and held the Panthers to 151 yards of total offense.
Giants vs. Texans spread, moneyline, total
Houston hosts New York on Saturday, and the Texans are favored to win at Caesars Sportsbook.
| Caesars Sportsbook odds | Spread | Moneyline | Total |
| Giants | +5.5 | +205 | OVER 35.5 |
| Texans | -5.5 | -250 | UNDER 35.5 |
Unlike many starting QBs, C.J. Stroud played for Houston and connected with RB Tank Dell for a TD pass in a 20-12 win over Pittsburgh. This was the second preseason tilt for Houston, which opened up preseason play with a loss to Chicago in the Hall of Fame Game.
The Giants defeated the Lions, 14-3, in their opener last Thursday. Tommy DeVito and Drew Lock split QB duties for New York. Starting QB Daniel Jones did not play, and rookie WR Malik Nabers suffered a minor ankle sprain. The former LSU product returned to practice over the weekend and hauled in a long TD pass from Jones.
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Falcons vs. Ravens odds
Atlanta takes on Baltimore on Saturday, and we've got odds on the game from Bet365:
| Bet365 odds | Spread | Moneyline | Total |
| Falcons | -2 | -140 | OVER 35.5 |
| Ravens | +2 | +120 | UNDER 35.5 |
Atlanta began its preseason with a 20-13 loss to Miami. Starting quarterback Kirk Cousins did not play, as he continues to recover from a torn Achilles in Minnesota last year. While he's not expected to play in the preseason, Cousins said he'll be ready for Week 1 of the regular season.
Devin Leary and Josh Johnson took snaps at QB in Baltimore's opening loss to Philadelphia. Leary scored the lone TD for the Ravens on a one-yard plunge. Veteran kicker Justin Tucker converted on both field-goal attempts and led Baltimore with seven total points.
Bengals vs. Bears
Here are Bengals vs. Bears odds from FanDuel.
| FanDuel odds | Spread | Moneyline | Total |
| Bengals | +2.5 | +135 | OVER 36.5 |
| Bears | -2.5 | -155 | UNDER 36.5 |
Cincy QB Joe Burrow continues to recover from a wrist injury suffered last season, but he looked good in the season opener against Tampa Bay. Burrow connected on five of seven pass attempts for 51 yards and a TD pass to Tee Higgins in the 17-14 loss.
Meanwhile, No. 1 draft pick Caleb Williams impressed in his preseason debut against Buffalo. The former USC QB went 4-of-7 for 95 passing yards and added a 13-yard scramble in a 33-6 win over the Bills.
Packers vs. Broncos spread, moneyline, total
Check out Packers vs. Broncos odds from DraftKings.
| DraftKings odds | Spread | Moneyline | Total |
| Packers | +3.5 | +154 | OVER 37.5 |
| Broncos | -3.5 | -185 | UNDER 37.5 |
Green Bay QB Jordan Love will not play in this game after a sizzling start to the preseason in a 23-10 win over Cleveland. Love took three snaps and connected with Dontayvion Wicks for a 65-yard scoring strike on his final play.
First-round draft pick Bo Nix also played well in a 34-30 win over Indianapolis. He went 15-of-21 for 125 passing yards and a TD pass to Marvin Mims Jr. to lead Denver to the victory.
Point spreads for other Week 2 NFL Preseason games
Here's a look at point spreads via DraftKings for the remaining Week 2 NFL Preseason games.
- Chiefs -3.5 vs. Lions
- Browns -2.5 vs. Vikings
- Jets -3.5 vs. Panthers
- Colts -3.5 vs. Cardinals
- Dolphins -1.5 vs. Commanders
- Steelers -1.5 vs. Bills
- Titans -2.5 vs. Seahawks
- Rams -1.5 vs. Chargers
- Jaguars -2.5 vs. Buccaneers
- Raiders -4 vs. Cowboys
- 49ers -1.5 vs. Saints